Most of the supermutants carry heavy automatic weapons that can shred through multiple characters at once, *AND* these weapons have the range of a hunting rifle (which is the gun with the longest range at this point). And holy hell, it's a massive spike in difficulty. I'm glad I decided to do this, because I'm having a blast! The only problem is that I'm now up to Mission 8 (St Louis), and am encountering Supermutants for the first time. I've decided to give it another chance, and am currently playing it on Hard. I was also overwhelmed by the sheer variety of firearms. I had just played Fallout 1, and was expecting more of the same, so the change in gameplay was unexpected. I must have played through half a mission before putting it on the backburner.
I picked up Fallout: Tactics over a decade ago.